HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 67333443, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Methyl 4-chloro-3-nitrobenzoate | HCID 735797 | — |
| Reactant | N-Boc-N-methylethylenediamine | HCID 2756424 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67333443 | HCID 67333443 | 103.7% |
Reaction Steps
4-[2-(tert-Butoxycarbonyl-methyl-amino)-ethylamino]-3-nitro-benzoic acid methyl ester (1.7 g) was prepared by following General Procedure A starting from 4-chloro-3-nitro-benzoic acid methyl ester (1 g), (2-amino-ethyl)-methyl-carbamic acid tert-butyl ester (1.2 g) and DIEA (1.7 mL) in THF (20 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-df5c5c452b004db9ac2fa9aaaf4b6c15 |
| Source note | uspto-grants-2014_06 |