HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutanol → HCID 54757864, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutanol | HCID 6560 | — |
| Reactant | 3-Hydroxy-2-(3-(2-((triisopropylsilyl)oxy)ethyl)benzyl)cyclopent-2-enone | HCID 54757863 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 54757864 | HCID 54757864 | 81% |
Reaction Steps
A mixture containing 46 (0.294 g, 0.757 mmol), paratoluensolfonic acid (0.005 g), i-butanol (1.0 mL) and benzene (4.0 mL) was heated to reflux for 12 h. The reaction mixture was then concentrated and the residue so obtained was purified by silica gel column chromatography using 5% of methanol in dichloromethane as eluent, obtaining the desired compound. Yield: 81%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530520B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-e18e156ee1644ee4a48f6aade48e5544 |
| Source note | uspto-grants-2013_09 |