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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411614Generated: October 31, 2026

Lansoprazole → HCID 10128985, compound

https://huagongshe.com/reaction/411614

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLansoprazoleHCID 3883—
ReactantTriethylamineHCID 8471—
Reactant4-UREIDO-BENZENESULFONYL CHLORIDEHCID 2760889—
SolventDichloromethaneHCID 6344—
ProductHCID 10128985HCID 10128985—

Reaction Steps

2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole (185 mg) dissolved in 30 ml of dichloromethane and 0.4 ml of triethylamine was added to 128 mg of N-[4-(chlorosulfonyl)phenyl]urea. The reaction mixture was stirred at room temperature overnight. The reaction mixture was washed with water and 0.1N sodium bicarbonate solution.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559167B1
Source datasetuspto-grants-2003_05
ORD IDord-96d30534e1294c18bfb274f277025208
Source noteuspto-grants-2003_05