HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lansoprazole → HCID 10128985, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lansoprazole | HCID 3883 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-UREIDO-BENZENESULFONYL CHLORIDE | HCID 2760889 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10128985 | HCID 10128985 | — |
Reaction Steps
2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole (185 mg) dissolved in 30 ml of dichloromethane and 0.4 ml of triethylamine was added to 128 mg of N-[4-(chlorosulfonyl)phenyl]urea. The reaction mixture was stirred at room temperature overnight. The reaction mixture was washed with water and 0.1N sodium bicarbonate solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06559167B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-96d30534e1294c18bfb274f277025208 |
| Source note | uspto-grants-2003_05 |