HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418806, compound → 4-methyl-3-[(1H-pyrazol-5-ylamino)methylidene]-1H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418806 | HCID 178418806 | — |
| Reactant | HCID 178423596 | HCID 178423596 | — |
| Reactant | HCID 178517101 | HCID 178517101 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-methyl-3-[(1H-pyrazol-5-ylamino)methylidene]-1H-indol-2-one | HCID 178423594 | — |
Reaction Steps
The named compound is prepared by substituting E & Z-3-[(hydroxy)-methylene]-4-methyl-1,3-dihydro-indol-2-one for E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-4-methyl-1,3-dihydro-indol-2-one (0.110 gms.) is reacted with 0.18 mL of 3-aminopyrazole by refluxing in tetrahydrofuran (2.5 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06559173B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-d73dafc4d154434296b12da3bbbbf17d |
| Source note | uspto-grants-2003_05 |