HCID 178418806, compound → HCID 178434876, compound

HRID 411690Notes

Reaction equation

HRID 411690 reaction equation
NC1C=CNN=1.O/[CH:8]=[C:9]1\[C:10](=[O:18])[NH:11][C:12]2[C:17]\1=[CH:16][CH:15]=[CH:14][CH:13]=2.[C:19]([C:23]1[O:27][C:26]([CH3:28])=[C:25]([C:29]2[CH:30]=[C:31]([NH2:34])[NH:32][N:33]=2)[CH:24]=1)([CH3:22])([CH3:21])[CH3:20]>O1CCCC1>[C:19]([C:23]1[O:27][C:26]([CH3:28])=[C:25]([C:29]2[CH:30]=[C:31]([NH:34][CH:8]=[C:9]3[C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[NH:11][C:10]3=[O:18])[NH:32][N:33]=2)[CH:24]=1)([CH3:22])([CH3:20])[CH3:21]

Participants

5

Reactant 3

HCID 178418806HCID 178418806, compoundHCID 178434878HCID 178434878, compoundHCID 178517101HCID 178517101, compound

Product 1

HCID 178434876HCID 178434876, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The named compound is prepared by substituting 5-(5-tert-butyl-2-methyl-furan-3-yl)-1H-pyrazol-3-ylamine for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one (0.100 gms.) is reacted with 0.2987 gms. of 5-(5-tert-butyl-2-methyl-furan-3-yl)-2H-pyrazol-3-ylamine by refluxing in tetrahydrofuran (2.5 mL).

Workup

  1. customThe named compound is prepared
  2. customin the reaction of Example 1

Sources & evidence

ORD record
ord-55664d1d10d541b2b941870d333073c6
Source dataset
uspto-grants-2003_05
Patent number
US06559173B1

Reaction notes

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