HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 63261691, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Reactant | phenylalaninol, (S)- | HCID 447213 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 63261691 | HCID 63261691 | — |
Reaction Steps
10.0 g of chloronicotinic acid were reacted with 9.7 g of phenylalaninol in 250 ml of CH2Cl2 in the presence of 13.0 g of EDC, 2.9 g of HOBT and 9.6 g of triethylamine analogously to Example 1c, 17.3 g (94%) of the product being obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562827B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-17ac732af2e14de7bdb33eddb3349769 |
| Source note | uspto-grants-2003_05 |