HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 70029060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | phenylalaninol, (S)- | HCID 447213 | — |
| Reactant | HCID 18536280 | HCID 18536280 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 70029060 | HCID 70029060 | — |
Reaction Steps
13 g of 2-(4-butoxycarbonylpiperazin-1-yl)nicotinic acid were dissolved in 150 ml of methylene chloride and 14.7 ml of triethylamine analogously to Example 1c and treated successively with 6.4 g of phenylalaninol, 1.9 g of HOBT and 8.11 g of EDC, 16.7 g (90%) of the product being obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562827B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-a2a3b0c2b53642a285a963d80a2e3fbf |
| Source note | uspto-grants-2003_05 |