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HRID41211

反应详情

EQUATION

反应方程式

HRID 41211 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：COC(=O)c1cc([C@H]2CCCN2c2ccc(F)cc2)c2oc(N3CCOCC3)cc(=O)c2c1
HCID86672433

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)c1cc(C2CCCN2c2ccc(F)cc2)c2oc(N3CCOCC3)cc(=O)c2c1
HCID86672434

未命名化合物

收率 83.3%

PROCEDURE

实验过程

Methyl 8-[(2R)-(1-(4-fluorophenyl)pyrrolidin-2-yl)]-2-morpholino-4-oxo-4H-chromene-6-carboxylate (119 mg, 0.26 mmol from 2 different batches) was reacted with sodium hydroxide to give 8-(1-(4-fluorophenyl)pyrrolidin-2-yl)-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid (enantiomer 2, 95 mg, 82%) as a yellow solid. Mass Spectrum: m/z [M+H]+=439.