Chloroform → HCID 18536351, compound

Participants

Reaction Steps

To a solution of 2-[4-(1-tert-butoxycarbonylpyrrolidin-3-yloxy)-phenoxymethyl]-1-(2-methoxyethyl)benzimidazole-5-carboxamidine (115 mg) in chloroform (3 ml) was added trifluoroacetic acid (3 ml), and the mixture was stirred at 5 min. The solvent was evaporated and to the obtained residue was added 1N hydrogen chloride-diethyl ether (2 ml). The solvent was evaporated and the obtained residue was washed with tetrahydrofuran and dried under reduced pressure to give the title compound (97 mg).

Provenance & Evidence