Hydrogen Bromide → 1,2,3,4-Tetrahydroisoquinolin-6-ol--hydrogen bromide (1/1)

Participants

Reaction Steps

6-Methoxy-1,2,3,4-tetrahydroisoquinoline (2.89 g) was dissolved in 48% aqueous hydrogen bromide solution (70 ml) and the mixture was refluxed for 2 hours. The solvent was evaporated and to the obtained residue were added ethanol and diethyl ether. The mixture was filtrated and dried under reduced pressure to give the title compound (3.93 g).

Provenance & Evidence