HCID 11226240, compound → HCID 11191164, compound

Participants

Reaction Steps

4-(2-Amidino-2,3,4,5-tetrahydro-1H-benz[c]azepin-8-yloxymethyl)-1-(pyridin-4-yl)piperidine-4-carboxylic acid ethyl ester dihydrochloride (150 mg) was dissolved in 6N-hydrochloric acid (2 ml), and the mixture was stirred under reflux for 3 hours. After completion of the reaction, insoluble material was removed and the solvent was evaporated. The residue was dried under reduced pressure to give the title compound (140 mg).

Provenance & Evidence