3,4-Diaminobenzonitrile → HCID 69698598, compound

Participants

Reaction Steps

To a solution of 3,4-diaminobenzonitrile (474 mg), 4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenoxyacetic acid (1.25 g) in tetrahydrofuran (50 ml) was added 1-ethoxycarbonyl-2-ethoxy-1,2-dihydroxyquinoline (1.06 g) with ice-cooling, and the mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was evaporated and to the obtained residue were added chloroform and hexane. The resultant solid was collected by filtration and dried under reduced pressure to give the title compound (1.55 g).

Provenance & Evidence