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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412620Generated: October 31, 2026

4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrile → HCID 18536365, compound

https://huagongshe.com/reaction/412620

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrileHCID 18536558—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18536365HCID 1853636599.8%

Reaction Steps

4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrile (3.64 g) was hydrogenated using 7.5% palladium carbon (1.1 g) in tetrahydrofuran (100 ml) at atmospheric pressure over 40 min. After completion of the reaction, the reaction mixture was filtered through celite, and the solvent was evaporated and the residue was dried under reduced pressure to give the title compound (3.274 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562828B1
Source datasetuspto-grants-2003_05
ORD IDord-4d083759dba04981bf370037b192c681
Source noteuspto-grants-2003_05