HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrile → HCID 18536365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrile | HCID 18536558 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18536365 | HCID 18536365 | 99.8% |
Reaction Steps
4-(Cyclohexylcarbamoylmethylamino)-3-nitrobenzonitrile (3.64 g) was hydrogenated using 7.5% palladium carbon (1.1 g) in tetrahydrofuran (100 ml) at atmospheric pressure over 40 min. After completion of the reaction, the reaction mixture was filtered through celite, and the solvent was evaporated and the residue was dried under reduced pressure to give the title compound (3.274 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562828B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-4d083759dba04981bf370037b192c681 |
| Source note | uspto-grants-2003_05 |