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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413142Generated: October 28, 2026

(4-Amino-3'-chloro-biphenyl-3-yl)-cyclopropyl-methanone → 1-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-1-propynyl-methanol

https://huagongshe.com/reaction/413142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Amino-3'-chloro-biphenyl-3-yl)-cyclopropyl-methanoneHCID 23509605—
ReactantHCID 178419101HCID 178419101—
Product1-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-1-propynyl-methanolHCID 23509634—

Reaction Steps

1-(4-Amino-3′-chloro-biphenyl-3-yl)-1-cyclopropyl-1-propynyl-methanol was prepared from (4-amino-3′-chloro-biphenyl-3-yl)-cyclopropyl-methanone and propynylmagnesium bromide according to Example 41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06566358B2
Source datasetuspto-grants-2003_05
ORD IDord-53847125d2b8483d95ae816528387484
Source noteuspto-grants-2003_05