HRID413495

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID143276

4-(2-(Methylamino)ethyl)pyridine

C8H12N2

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)C(=O)O

HCID7015127

未命名化合物

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)O

HCID10065151

未命名化合物

HCID10847814

未命名化合物

PRODUCTS

生成物

结构：CN(CCc1ccncc1)C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)/C=C/CC(C)(C)N

HCID9852273

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as in example 1 (except from step 3, see below) using 4-[2-(Methylamino)ethyl]pyridin, (2R)-2-(N-(tert-Butoxycarbonyl)-N-methylamino)-3-phenylpropionic acid, (2R)-2-(N-(tert-butoxycarbonyl)-N-methylamino)-3-(2-naphthyl)propionic acid and (2E)-5-(tert-Butoxycarbonylamino)-5-methylhex-2-enoic acid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e04ed25e12124a03b0a525cd351bb744
来源数据集: uspto-grants-2003_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06566337B1
来源说明: uspto-grants-2003_05

反应 SMILES

[CH3:1][NH:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1.C(O[C:16]([N:18]([C@H:20]([CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:21]([OH:23])=O)[CH3:19])=[O:17])(C)(C)C.C(O[C:36]([N:38]([C@H:40]([CH2:44][C:45]1[CH:54]=[CH:53][C:52]2[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=2)[CH:46]=1)C(O)=O)[CH3:39])=[O:37])(C)(C)C.C(OC([NH:62][C:63]([CH3:71])([CH3:70])[CH2:64]/[CH:65]=[CH:66]/C(O)=O)=O)(C)(C)C>>[CH3:39][N:38]([C@@H:40]([C:16](=[O:17])[N:18]([CH3:19])[C@@H:20]([C:21](=[O:23])[N:2]([CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1)[CH3:1])[CH2:24][C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[CH2:44][C:45]1[CH:54]=[CH:53][C:52]2[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=2)[CH:46]=1)[C:36](=[O:37])/[CH:66]=[CH:65]/[CH2:64][C:63]([NH2:62])([CH3:71])[CH3:70]