Hydrogen Bromide → HCID 18521530, compound

HRID 413679Notes

Reaction equation

HRID 413679 reaction equation
CO[CH2:3][C:4](=[C:6]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[CH2:10][CH2:9][C:8]2[CH:17]=[CH:18][CH:19]=[CH:20][C:7]1=2)[CH3:5].[BrH:21]>C(O)(=O)C.O>[CH3:5][C:4](=[C:6]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[CH2:10][CH2:9][C:8]2[CH:17]=[CH:18][CH:19]=[CH:20][C:7]1=2)[CH2:3][Br:21]

Participants

5

Reactant 2

HCID 260Hydrogen BromideHCID 18521522HCID 18521522, compound

Product 1

HCID 18521530HCID 18521530, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

The above ether (3.6 g, 13.6 mmol) was dissolved in acetic acid (40 ml) and 48% hydrobromic acid (20 ml) was added. After 7 days the mixture was diluted with water (200 ml) and extracted with benzene (100 ml). The organic phase was dried (MgSO4), filtered and the solvent was evaporated in vacuo to give 3.8 g of crude 5-(1-methyl-2-bromoethylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene.

Workup

  1. extractionextracted with benzene (100 ml)
  2. dry with materialThe organic phase was dried (MgSO4)
  3. filtrationfiltered
  4. customthe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-1fd6f54ea97b4a76815ec9e98541bcdf
Source dataset
uspto-grants-2003_05
Patent number
US06569849B1

Reaction notes

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