Ethanol → HCID 22611021, compound

HRID 413743Notes

Reaction equation

HRID 413743 reaction equation
[N+:1]([C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1)([O-])=O.O.O.O.O.O.O.O.O.O.[S-2].[Na+].[Na+].[Cl-].[NH4+].C(O)C>O>[NH2:1][C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 25517Ammonium ChlorideHCID 73972Sodium sulfide nonahydrateHCID 18522031HCID 18522031, compound

Product 1

HCID 22611021HCID 22611021, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2-nitro-N-(4-(2-thiazolylamino)phenyl)aniline (1.2 g, 3.8 mmol), sodium sulfide nona hydrate (4.61, 19.2 mmol), ammonium chloride (1.03 g, 19.2 mmol) and ethanol (40 ml) was stirred at reflux for 40 h. Water (50 ml) was added, the mixture was stirred and filtered. Yield 0.49 g, 46%. M.p. 184-186° C.

Workup

  1. temperatureat reflux for 40 h
  2. stirringthe mixture was stirred
  3. filtrationfiltered

Sources & evidence

ORD record
ord-031abc84e8544dfa85846c5813f7f54a
Source dataset
uspto-grants-2003_05
Patent number
US06569880B2

Reaction notes

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