3-Chlorobenzoic Acid → HCID 86742593, compound

HRID 414011Notes

Reaction equation

HRID 414011 reaction equation
[F:1][CH:2]([F:23])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH3:19])[C:4]=1[S:20][CH2:21][CH3:22].C1C=C(Cl)C=C(C(OO)=[O:32])C=1.C1C=C(Cl)C=C(C(O)=O)C=1>>[F:23][CH:2]([F:1])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:10])[F:11])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH3:19])[C:4]=1[S:20]([CH2:21][CH3:22])=[O:32]

Participants

4

Reactant 3

HCID 4473-Chlorobenzoic AcidHCID 70297m-Chloroperbenzoic acidHCID 14347929HCID 14347929, compound

Product 1

HCID 86742593HCID 86742593, compound

Procedure

Prepared from product of Example 5 (7.0 g, 19.6 mmol) and MCPBA (3.98 g of an 85% mixture with MCBA, 19.6 mmol) as described above. Recrystallization (ether/petroleum ether) afforded the product as a white solid (6.56 g).

Workup

  1. customRecrystallization (ether/petroleum ether)

Sources & evidence

ORD record
ord-eba0e4ca999c4246ab374096d301af79
Source dataset
uspto-grants-1988_12
Patent number
US04789395

Reaction notes

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