3-Chlorobenzoic Acid → HCID 86742596, compound

HRID 414014Notes

Reaction equation

HRID 414014 reaction equation
[F:1][CH:2]([F:27])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH3:19])[C:4]=1[S:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.C1C=C(Cl)C=C(C(OO)=[O:36])C=1.C1C=C(Cl)C=C(C(O)=O)C=1>>[F:27][CH:2]([F:1])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:10])[F:11])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH3:19])[C:4]=1[S:20]([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:36]

Participants

4

Reactant 3

HCID 4473-Chlorobenzoic AcidHCID 70297m-Chloroperbenzoic acidHCID 14347932HCID 14347932, compound

Product 1

HCID 86742596HCID 86742596, compound

Procedure

Prepared from product of Example 8 (6.1 g, 15.1 mmol) and MCPBA (2.9 g of an 85% mixture with MCBA, 15.1 mmol) as described above. Recrystallization (ether/petroleum ether) afforded the product as a white solid (4.46 g).

Workup

  1. customRecrystallization (ether/petroleum ether)

Sources & evidence

ORD record
ord-8df3d3a3d6c04167a67e1273f9f95d45
Source dataset
uspto-grants-1988_12
Patent number
US04789395

Reaction notes

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