3-Chlorobenzoic Acid → HCID 86742597, compound

HRID 414015Notes

Reaction equation

HRID 414015 reaction equation
[F:1][CH:2]([F:23])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH3:18])[C:4]=1[S:19][CH:20]([CH3:22])[CH3:21].C1C=C(Cl)C=C(C(OO)=[O:32])C=1.C1C=C(Cl)C=C(C(O)=O)C=1>>[F:23][CH:2]([F:1])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:10])[F:11])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH3:18])[C:4]=1[S:19]([CH:20]([CH3:22])[CH3:21])=[O:32]

Participants

4

Reactant 3

HCID 4473-Chlorobenzoic AcidHCID 70297m-Chloroperbenzoic acidHCID 14347934HCID 14347934, compound

Product 1

HCID 86742597HCID 86742597, compound

Procedure

Prepared from product of Example 10 (6.06 g, 16.96 mmol) and MCPBA (3.44 g of an 85% mixture with MCBA, 16.96 mmol) as described above. Recrystallization (ether/petroleum ether) afforded the product as a white solid (4.65 g).

Workup

  1. customRecrystallization (ether/petroleum ether)

Sources & evidence

ORD record
ord-85a490ce505f4cbb86ee4577c49f4c50
Source dataset
uspto-grants-1988_12
Patent number
US04789395

Reaction notes

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