3-Chlorobenzoic Acid → HCID 86742599, compound

HRID 414017Notes

Reaction equation

HRID 414017 reaction equation
[F:1][CH:2]([F:26])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH:19]([CH3:21])[CH3:20])[C:4]=1[S:22][CH:23]([CH3:25])[CH3:24].C1C=C(Cl)C=C(C(OO)=[O:35])C=1.C1C=C(Cl)C=C(C(O)=O)C=1>>[F:26][CH:2]([F:1])[C:3]1[N:8]=[C:7]([C:9]([F:12])([F:10])[F:11])[C:6]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:5]([CH2:18][CH:19]([CH3:21])[CH3:20])[C:4]=1[S:22]([CH:23]([CH3:25])[CH3:24])=[O:35]

Participants

4

Reactant 3

HCID 4473-Chlorobenzoic AcidHCID 70297m-Chloroperbenzoic acidHCID 14347936HCID 14347936, compound

Product 1

HCID 86742599HCID 86742599, compound

Procedure

Prepared from product of Example 12 (5.97 g, 14.95 mmol) and MCPBA (3.03 g of an 85% mixture with MCBA, 14.95 mmol) as described above. Recrystallization (ether/petroleum ether) afforded the product as a white solid (4.03 g).

Workup

  1. customRecrystallization (ether/petroleum ether)

Sources & evidence

ORD record
ord-98a4cfcd84664a78a8b504fbb794cfb0
Source dataset
uspto-grants-1988_12
Patent number
US04789395

Reaction notes

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