HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 21282002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzoyl chloride | HCID 101856 | — |
| Reactant | 2-Amino-1-(5-methylthiophen-2-yl)ethan-1-one--hydrogen chloride (1/1) | HCID 13583304 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21282002 | HCID 21282002 | 83.1% |
Reaction Steps
In a manner similar to Example 1, the reaction of 2-amino-1-(5-methylthienyl)ethanone hydrochloride (2.6 g, 0.014 mole) in methylene chloride (75 ml) with 3,5-bis(trifluoromethyl)benzoyl chloride (3.8 g, 0.014 mole) and 2N sodium hydroxide solution (13.7 ml) yielded 4.6 g of N-[2-(5-methylthienyl)-2-oxoethyl]-3,5-bis(trifluoromethyl)benzamide as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04791124 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-c15b897c09b0466a8e7d04eff015e694 |
| Source note | uspto-grants-1988_12 |