HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → Benzoyl chloride, 2,3-dichloro-4,5-difluoro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,3-Dichloro-4,5-difluorobenzoic acid | HCID 13938036 | — |
| Product | Benzoyl chloride, 2,3-dichloro-4,5-difluoro- | HCID 10999320 | — |
Reaction Steps
A solution of 2,3-dichloro-4,5-difluorobenzoic acid (9.3 g) and dimethylformamide (0.013 ml) in thionyl chloride (40 ml) was refluxed for 2.5 hours, and then concentrated. The resulting residue was purified by distillation in nitrogen atmosphere to give the title compound (8.7 g) as pale yellow oil, bp 123°-126° C./40 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04791225 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-2cf3c5da3c9a43c6a773405b46f75f3b |
| Source note | uspto-grants-1988_12 |