反应详情

A solution of 3-bromo-2-chloro-4,5-difluorobenzoic acid (9.0 g) in thionyl chloride (33 ml) was refluxed for 2.5 hours, and then concentrated. The resulting residue was purified by distillation to give the title compound (8.8 g), bp 109° C./22 mmHg.

1. concentrationconcentrated
2. distillationThe resulting residue was purified by distillation