HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Bromo-2-chloro-4,5-difluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Bromo-2-chloro-4,5-difluorobenzoic acid | HCID 9838347 | — |
| Product | 3-Bromo-2-chloro-4,5-difluorobenzoyl chloride | HCID 14071797 | — |
Reaction Steps
A solution of 3-bromo-2-chloro-4,5-difluorobenzoic acid (9.0 g) in thionyl chloride (33 ml) was refluxed for 2.5 hours, and then concentrated. The resulting residue was purified by distillation to give the title compound (8.8 g), bp 109° C./22 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04791225 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-18d29e282d0a4a95baf47415037746ea |
| Source note | uspto-grants-1988_12 |