Hydrochloric Acid → 2-[(4-Ethylphenyl)methyl]benzoic acid

HRID 414471Notes

Reaction equation

HRID 414471 reaction equation
[Sn].[CH2:2]([C:4]1[CH:20]=[CH:19][C:7]([C:8]([C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([OH:14])=[O:13])=O)=[CH:6][CH:5]=1)[CH3:3].Cl>C(O)(=O)C>[CH2:2]([C:4]1[CH:20]=[CH:19][C:7]([CH2:8][C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([OH:14])=[O:13])=[CH:6][CH:5]=1)[CH3:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 708522-(4-Ethylbenzoyl)benzoic acidHCID 5352426Tin atom

Product 1

HCID 178586942-[(4-Ethylphenyl)methyl]benzoic acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

(b.2) (Alternative reduction procedure) Tin powder (15 g) is added to a solution of 2-(4-ethylbenzoyl)benzoic acid (3 g) in acetic acid (50 ml). Concentrated hydrochloric acid (5 ml) is added and the mixture is refluxed for 3 hours, then decanted from the undissolved tin, cooled, and diluted with water to afford a precipitate of 2-(4-ethylbenzyl)benzoic acid.

Workup

  1. temperaturethe mixture is refluxed for 3 hours
  2. customdecanted from the undissolved tin
  3. temperaturecooled
  4. additiondiluted with water

Sources & evidence

ORD record
ord-0d9c844bc618407495beff66021ca414
Source dataset
uspto-grants-1988_12
Patent number
US04792551

Reaction notes

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