Phosphoric Acid → HCID 86122419, compound

HRID 414479Notes

Reaction equation

HRID 414479 reaction equation
[P:1](=[O:5])([OH:4])([OH:3])[OH:2].[CH:6]1[C:19]2[C:10](=[CH:11][C:12]3[C:17]([C:18]=2[O:20][CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25])=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:9]=[CH:8][CH:7]=1.C(OCC)C>CO>[P:1]([OH:5])([OH:4])([OH:3])=[O:2].[CH:16]1[C:17]2[C:12](=[CH:11][C:10]3[C:19]([C:18]=2[O:20][CH2:21][CH2:22][CH2:23][N:24]([CH3:25])[CH3:26])=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:13]=[CH:14][CH:15]=1

Participants

5

Reactant 3

HCID 1004Phosphoric AcidHCID 3283Diethyl EtherHCID 416338HCID 416338, compound

Product 1

HCID 86122419HCID 86122419, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A twofold stoichiometric excess of 3% phosphoric acid in methanol is added to a methanolic solution of 1.0 g. of 1-(9-anthryloxy)-3-dimethylaminopropane. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 1-(9-anthryloxy)-3-dimethylaminopropane phosphate, m.p. 196°-200° C.

Workup

  1. filtrationThe product is filtered
  2. washwashed with ether, air
  3. customdried
  4. customrecrystallized

Sources & evidence

ORD record
ord-bdbe9fde43d8473fbf3b322b15f61767
Source dataset
uspto-grants-1988_12
Patent number
US04792551

Reaction notes

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