Potassium Carbonate → 1-(9-Anthryloxy)-2-aminoethane

HRID 414480Notes

Reaction equation

HRID 414480 reaction equation
C(O)(=O)/C=C\C(O)=O.[CH:9]1[C:22]2[C:13](=[CH:14][C:15]3[C:20]([C:21]=2[O:23][CH2:24][CH2:25][NH2:26])=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:12]=[CH:11][CH:10]=1.C(=O)([O-])[O-].[K+].[K+]>CCOCC>[CH:19]1[C:20]2[C:15](=[CH:14][C:13]3[C:22]([C:21]=2[O:23][CH2:24][CH2:25][NH2:26])=[CH:9][CH:10]=[CH:11][CH:12]=3)[CH:16]=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 867426221-(9-Anthryloxy)-2-aminoethane maleate

Product 1

HCID 143732341-(9-Anthryloxy)-2-aminoethane

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

1.0 g of 1-(9-anthryloxy)-2-aminoethane maleate suspended in 50 ml of ether is stirred with a twofold stoichiometric excess of dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 1-(9-anthryloxy)-2-aminoethane as the free base.

Workup

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-da6b8e4769944bfe9a1da04bd83e514f
Source dataset
uspto-grants-1988_12
Patent number
US04792551

Reaction notes

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