Hydrocarbostyril → HCID 14373287, compound

HRID 414556Notes

Reaction equation

HRID 414556 reaction equation
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[Cl-].[Cl-].[Cl-].[Al+3].[NH:14]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:18][CH2:17][C:15]1=[O:16]>>[N:4]1[CH:5]=[CH:6][CH:7]=[C:2]([C:1]([C:21]2[CH:20]=[C:19]3[C:24](=[CH:23][CH:22]=2)[NH:14][C:15](=[O:16])[CH2:17][CH2:18]3)=[O:8])[CH:3]=1

Participants

4

Reactant 3

HCID 64796HydrocarbostyrilHCID 82604Nicotinoyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 14373287HCID 14373287, compound

Procedure

A mixture of 1.42 g of nicotinoyl chloride (a compound of Formula A2), 6 g of aluminum trichloride and 1 g of 3,4-dihydrocarbostyril were reacted in the same manner as in Preparation 1. The product was isolated similarly giving 6-(3-pyridylcarbonyl)-3,4-dihydrocarbostyril, m.p. 195°-202° C.

Workup

  1. customwere reacted in the same manner as in Preparation 1

Sources & evidence

ORD record
ord-1db6e9d9e8e946639cbed0b17667e50e
Source dataset
uspto-grants-1988_12
Patent number
US04792561

Reaction notes

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