HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril acetate | HCID 19854608 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride | HCID 19854738 | — |
Reaction Steps
6-[3-(imidazol-1-yl)propyl]-3,4-dihydrocarbostyril acetate (1.0 g) is dissolved in 50 ml of methanol and a stoichiometric amount of a solution of hydrochloric acid in methanol is added. The solvent is removed under vacuum and the residue recrystallised from a mixture of methanol and ethyl acetate to yield 6-[3-(imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04792561 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-04014dc515f34e7791ab7d5edfc64f36 |
| Source note | uspto-grants-1988_12 |