HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[([1,1'-Biphenyl]-4-yl)oxy]butan-1-amine--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | HCID 13957280 | HCID 13957280 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[([1,1'-Biphenyl]-4-yl)oxy]butan-1-amine--hydrogen chloride (1/1) | HCID 13957281 | — |
Reaction Steps
A twofold stoichiometric excess of 3% hydrochloric acid in methanol is added to a methanolic solution of 1.0 g. of 4-(4-biphenyloxy)-1-aminobutane. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 4-(4-biphenyloxy)-1-aminobutane hydrochloride, m.p. 202°-205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04792570 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-a13de8ef933b41629c9f4289901c9ff5 |
| Source note | uspto-grants-1988_12 |