Sulfuric Acid → HCID 21281345, compound

HRID 414621Notes

Reaction equation

HRID 414621 reaction equation
C(O)(=O)C.[C:5]1([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])=[CH:7][CH:6]=1.[S:28](=[O:32])(=[O:31])([OH:30])[OH:29]>O>[S:28](=[O:30])(=[O:29])([OH:32])[OH:31].[C:5]1([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:6]=[CH:7][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]([CH3:20])[CH3:21])=[CH:9][CH:10]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 70418201HCID 70418201, compound

Product 1

HCID 21281345HCID 21281345, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

7-(4-biphenyloxy)-1-dimethylaminoheptane acetate (1.0 g) is dissolved in 50 ml water containing a stoichiometric equivalent of sulfuric acid, and the solution evaporated to dryness. The product is suspended in ethanol and filtered, air dried and recrystallized from methanol/acetone to yield 7-(4-biphenyloxy)-1-dimethylaminoheptane bisulfate.

Workup

  1. customthe solution evaporated to dryness
  2. filtrationfiltered
  3. customair dried
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-9c9140c1ec3f4179b0c7f2a550a92398
Source dataset
uspto-grants-1988_12
Patent number
US04792570

Reaction notes

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