m-Chloroperbenzoic acid → 2-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

HRID 414718Notes

Reaction equation

HRID 414718 reaction equation
[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21][C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2].ClC1C=C(C=CC=1)C(OO)=[O:28]>C(Cl)Cl>[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21](=[O:28])[C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 212803642-(4-Ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole

Product 1

HCID 212803682-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2-(4-ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole (0.01 mole) is dissolved in CH2Cl2 solution (100 ml) at 0° C. and treated with m-chloroperoxybenzoic acid (0.01 mole) for 0.5 hours. The solution is then washed with sodium carbonate solution and dried (MgSO4). Purification by chromatography on silica gives the title compound.

Workup

  1. washThe solution is then washed with sodium carbonate solution
  2. dry with materialdried (MgSO4)
  3. customPurification by chromatography on silica

Sources & evidence

ORD record
ord-1180dd7dea3f4b298b1f3583e2c95571
Source dataset
uspto-grants-1988_12
Patent number
US04794123

Reaction notes

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