Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorosulfonic acid → 4-(2,2,2-Trifluoroacetamido)benzene-1-sulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorosulfonic acid | HCID 24638 | — |
| 반응물 | 2,2,2-Trifluoro-N-phenylacetamide | HCID 67881 | — |
| 생성물 | 4-(2,2,2-Trifluoroacetamido)benzene-1-sulfonyl chloride | HCID 21280582 | — |
반응 단계
Chlorosulfonic acid (100 g.) was cooled to 0° C. and trifluoroacetanilide (30 g.) was added portionwise with vigorous stirring keeping the temperature below +5° C. The reaction was stirred at room temperature overnight, and cautiously poured onto ice. The white solid produced was filtered, washed copiously with water, and dried to give 4-trifluoroacetamido benzenesulfonyl chloride (39.14 gl)(m.r. 143°-146° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04794196 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-ed5937b650f7415296cb11e2862453de |
| 출처 메모 | uspto-grants-1988_12 |