Methanol → HCID 14349152, compound

HRID 414836Notes

Reaction equation

HRID 414836 reaction equation
C([O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)C1C=CC=CC=1.[C:16]1([OH:22])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[CH3:23]O>[Pd]>[CH3:23][C:10]([CH3:11])([CH2:15][CH2:14][CH2:13][CH3:12])[C:9]([C:18]1[CH:17]=[C:16]([OH:22])[CH:21]=[CH:20][CH:19]=1)=[O:8]

Participants

5

Reactant 3

HCID 887MethanolHCID 996PhenolHCID 7657Dibenzyl ether

Product 1

HCID 14349152HCID 14349152, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The benzyl ether of the desired phenol (26 g) was taken in methanol (150 ml) and this solution was hydrogenated in a Parr apparatus under an atmosphere of hydrogen (45-50 lbs./sq.in.) in the presence of 10% palladium on charcoal (10 g). After 20-24 hours, the suspension was filtered on celite; all methanol was removed to obtain the desired phenol in about 83% yield (15.4 g) as a coloress liquid.

Workup

  1. filtrationthe suspension was filtered on celite
  2. customall methanol was removed

Sources & evidence

ORD record
ord-ea4a23cde1f74e8fbace4d17864417bf
Source dataset
uspto-grants-1988_12
Patent number
US04794188

Reaction notes

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