HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 86633098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Nipecotic Acid | HCID 4498 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | HCID 86633098 | HCID 86633098 | — |
Reaction Steps
To a solution of piperidine-3-carboxylic acid (10.7 g, 83 mmol) in ethanol (40 mL) was added thionyl chloride (22.5 mL) at 0° C. dropwise, the reaction mixture was refluxed overnight. Then the mixture was evaporated at reduced pressure to give 3-(ethoxycarbonyl)piperidinium hydrochloride. (13 g, Y: 100%). LC-MS (ESI) (m/z): 158 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088760B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-54e08df1ea054b248c650d8d84d37470 |
| Source note | uspto-grants-2012_01 |