Sulfuric acid magnesium salt (1:1) → HCID 86633720, compound

Participants

Reaction Steps

The method of Part B of Example 1 was used to hydrogenate 2-chloro-3-nitro-N-(tetrahydro-2H-pyran-4-ylmethyl)quinolin-4-amine (7 g, 20 mmol) with the modifications that the reaction was stopped after four hours, and magnesium sulfate was added to the mixture before filtration. 2-Chloro-N4-(tetrahydro-2H-pyran-4-ylmethyl)quinoline-3,4-diamine (5 g) was isolated as a sticky, amber solid.

Provenance & Evidence