HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-(bromomethyl)-1,3-benzothiazole → 3-(5-Bromo-benzothiazol-2-ylmethoxy)-2,6-difluoro-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-(bromomethyl)-1,3-benzothiazole | HCID 14458642 | — |
| Reactant | 2,6-Difluoro-3-hydroxybenzamide | HCID 45120136 | — |
| Product | 3-(5-Bromo-benzothiazol-2-ylmethoxy)-2,6-difluoro-benzamide | HCID 46237014 | 81% |
Reaction Steps
Synthesised from 2,6-difluoro-3-hydroxybenzenecarboxamide and 5-bromo-2-(bromomethyl)-1,3-benzothiazole, according to Method B, scheme 2. Yield 81%, mp 244-246° C., HPLC-MS (method 1): m/z 399, 401 [M+H]+, Rt=3.98 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088791B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-fb2c0cf19dc74dcbbe4151f8976649d8 |
| Source note | uspto-grants-2012_01 |