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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416049Generated: October 27, 2026

2,3-Dichloro-4-hydroxybenzaldehyde → 3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)prop-2-en-1-one

https://huagongshe.com/reaction/416049

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichloro-4-hydroxybenzaldehydeHCID 528380—
Reactant1-(5-(4-(Trifluoromethoxy)phenyl)thien-2-yl)ethanoneHCID 59180351—
Product3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)prop-2-en-1-oneHCID 66623914—

Reaction Steps

3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)-ethanone and 2,3-dichloro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is crystallized from acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-9f175dfda4aa4822bbc3e6eeb6b28b3b
Source noteuspto-grants-2012_01