3-(2,3-Dichloro4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one → 3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)propan-1-one

HRID 416055Notes

Reaction equation

HRID 416055 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([OH:9])[CH:5]=[CH:4][C:3]=1[CH:10]=[CH:11][C:12]([C:14]1[S:15][C:16]([C:19]2[CH:24]=[CH:23][C:22]([S:25][CH3:26])=[CH:21][CH:20]=2)=[CH:17][CH:18]=1)=[O:13]>O1CCCC1>[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([OH:9])[CH:5]=[CH:4][C:3]=1[CH2:10][CH2:11][C:12]([C:14]1[S:15][C:16]([C:19]2[CH:20]=[CH:21][C:22]([S:25][CH3:26])=[CH:23][CH:24]=2)=[CH:17][CH:18]=1)=[O:13]

Participants

3

Reactant 1

HCID 666239353-(2,3-Dichloro4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one

Product 1

HCID 591803113-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)propan-1-one

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)propan-1-one is prepared from 3-(2,3-dichloro-4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one according to general procedure C in solution in tetrahydrofuran.

Sources & evidence

ORD record
ord-5351cd744a234f27b99ad37791d02758
Source dataset
uspto-grants-2012_01
Patent number
US08088819B2

Reaction notes

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