HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloro-4-hydroxybenzaldehyde → 3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(3-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloro-4-hydroxybenzaldehyde | HCID 528380 | — |
| Reactant | 1-[5-[3-(Trifluoromethyl)phenyl]-2-thienyl]ethanone | HCID 4191493 | — |
| Product | 3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(3-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one | HCID 66624393 | — |
Reaction Steps
3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(3-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(3-(trifluoromethyl)phenyl)thien-2-yl)ethanone and 2,3-dichloro-4-hydroxybenzaldehyde according to general procedure B, at 50° C. for 30 hours. The evaporation residue is purified by silica-gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088819B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b9e571a65dff4819a582bcc515451889 |
| Source note | uspto-grants-2012_01 |