HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 25061283, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | tert-Butyl 2-bromo-2-methylpropionate | HCID 90290 | — |
| Reactant | HCID 59180337 | HCID 59180337 | — |
| Product | HCID 25061283 | HCID 25061283 | — |
Reaction Steps
Tert-butyl 2-(2,6-dimethyl-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)-phenoxy)-2-methylpropanoate is prepared from 3-(4-hydroxy-3,5-dimethylphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-one according to general procedure D, using 15 equivalents of tert-butyl bromoisobutyrate and 15 equivalents of potassium carbonate added in portions of 3 equivalents in the course of the reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088819B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-72aa4f8f5f014ee1823cf2c5916c20bd |
| Source note | uspto-grants-2012_01 |