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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416097Generated: October 30, 2026

Potassium Carbonate → HCID 25061283, compound

https://huagongshe.com/reaction/416097

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactanttert-Butyl 2-bromo-2-methylpropionateHCID 90290—
ReactantHCID 59180337HCID 59180337—
ProductHCID 25061283HCID 25061283—

Reaction Steps

Tert-butyl 2-(2,6-dimethyl-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)-phenoxy)-2-methylpropanoate is prepared from 3-(4-hydroxy-3,5-dimethylphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-one according to general procedure D, using 15 equivalents of tert-butyl bromoisobutyrate and 15 equivalents of potassium carbonate added in portions of 3 equivalents in the course of the reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-72aa4f8f5f014ee1823cf2c5916c20bd
Source noteuspto-grants-2012_01