Trifluoroacetic acid → HCID 59180328, compound

Participants

Reaction Steps

2-(2,3-Dichloro-4-(3-oxo-3-(5-phenylthien-2-yl)propyl)phenoxy)-2-methylpropanoic acid is prepared from tert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-phenylthien-2-yl)propyl)phenoxy)-2-methylpropanoate according to general procedure E using 12 equivalents of trifluoroacetic acid. After stirring for 12 hours at room temperature, the reaction mixture is washed with water and then the dichloromethane is removed by evaporation under reduced pressure.

Provenance & Evidence