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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416112Generated: October 30, 2026

Benzyl Bromide → HCID 59180346, compound

https://huagongshe.com/reaction/416112

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantSodium hydrideHCID 24758—
ReactantHCID 25059981HCID 25059981—
ProductHCID 59180346HCID 59180346—

Reaction Steps

2-(4-(3-(Benzyloxy)-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)-2-fluoro-phenoxy)butanoic acid is prepared from 2-(2-fluoro-4-(3-hydroxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)butanoic acid using 2.1 equivalents of sodium hydride and 2.1 equivalents of benzyl bromide according to general procedure H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-47e0b3b1a88e453b85d35c7fafb0e0b0
Source noteuspto-grants-2012_01