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Acetylpyrazine → N-(2-Aminophenyl)-4-((4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetylpyrazine | HCID 30914 | — |
| 反応物 | 1-{2-Methylimidazo[1,2-a]pyridin-3-yl}ethan-1-one | HCID 2735255 | — |
| 反応物 | N-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamide | HCID 44570891 | — |
| 生成物 | N-(2-Aminophenyl)-4-((4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide | HCID 58930542 | — |
反応手順
Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material the ketone 333 (Table 11). Characterization of the title compound is provided in the Table 12.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08088805B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-67076c2045014952bd28ffe83898422e |
| 出典メモ | uspto-grants-2012_01 |