反应详情

2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethanesulfonic acid (1-isopropyl-piperidin-4-yl)-methyl-amide was prepared by an analogous procedure as described for example 1 i) starting from 171.3 mg (1.1 mmol) (1-isopropyl-piperidin-4-yl)-methyl-amine and 300 mg (1 equiv.) 2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethanesulfonyl chloride. 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethanesulfonic acid (1-isopropyl-piperidin-4-yl)-methyl-amide was obtained as a light yellow foam. Yield: 385 mg MS (ES+): m/e=394.

1. custom2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethanesulfonic acid (1-isopropyl-piperidin-4-yl)-methyl-amide was prepared by an analogous procedure