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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 417034Generated: October 30, 2026

HCID 86645714, compound → HCID 86645713, compound

https://huagongshe.com/reaction/417034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86645714HCID 86645714—
SolventSodium HydroxideHCID 14798—
ProductHCID 86645713HCID 8664571366.1%

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(3-acetyl-5-(2,3-dihydro-benzo[1,4]-dioxin-6-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (330 mg, 0.5 mmol) and 1.0 N aqueous sodium hydroxide (10 mL) to afford 4-[3-[6-(3-acetyl-5-(2,3-dihydro-benzo[1,4]dioxin-6-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (200 mg, 61%) as a off-white solid: ES(+)-HRMS m/e calcd for C35H40O9 (M+Na)+ 627.2564. found 627.2560.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088936B2
Source datasetuspto-grants-2012_01
ORD IDord-5e66ffa629fa4d92bd3da89019b17268
Source noteuspto-grants-2012_01