HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86645714, compound → HCID 86645713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86645714 | HCID 86645714 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 86645713 | HCID 86645713 | 66.1% |
Reaction Steps
A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(3-acetyl-5-(2,3-dihydro-benzo[1,4]-dioxin-6-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (330 mg, 0.5 mmol) and 1.0 N aqueous sodium hydroxide (10 mL) to afford 4-[3-[6-(3-acetyl-5-(2,3-dihydro-benzo[1,4]dioxin-6-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (200 mg, 61%) as a off-white solid: ES(+)-HRMS m/e calcd for C35H40O9 (M+Na)+ 627.2564. found 627.2560.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088936B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-5e66ffa629fa4d92bd3da89019b17268 |
| Source note | uspto-grants-2012_01 |