Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 41725Generated: October 29, 2026

Trifluoroacetic acid → HCID 86660476, compound

https://huagongshe.com/reaction/41725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86660477HCID 86660477—
SolventDichloromethaneHCID 6344—
ProductHCID 86660476HCID 8666047699%

Reaction Conditions

Temperature0 °C

Reaction Steps

TFA (1.6 ml) was dropped into an ice-cooled solution of octadeca-9,12-dienoic acid (E)-3-adamantan-1-yl-4′-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester (110 mg, 0.159 mmol) in DCM (1.6 ml) and the resulting solution was stirred for 30 min at 0° C. The solvent was removed under reduced pressure to obtain the title compound as a white solid (100 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08530517B2
Source datasetuspto-grants-2013_09
ORD IDord-45c5b184600743c9a414bb750fa959a8
Source noteuspto-grants-2013_09