Hydrochloric Acid → HCID 178516620, compound

HRID 41766Notes

Reaction equation

HRID 41766 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=4[F:22])[C:13](=[O:23])[CH:12](C(OCC)=O)[C:11]3=[O:29])=[CH:9][C:4]=2[N:3]=[CH:2]1.Cl>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=4[F:22])[C:13](=[O:23])[CH2:12][C:11]3=[O:29])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178470024HCID 178470024, compound

Product 1

HCID 178516620HCID 178516620, compound

Procedure

The compound was synthesized starting from ethyl 1-(1H-benzo[d]imidazol-5-yl)-2,4-dioxo-5-(2,3-difluorophenyl)pyrrolidine-3-carboxylate (which may be prepared in accordance with the procedure described for Intermediate 6; 0.082 g, 0.205 mmol) and 5 N aqueous hydrochloric acid (3 ml) according to the method described in Method 1, step 3.

Workup

  1. customThe compound was synthesized
  2. custommay be prepared in accordance with the procedure

Sources & evidence

ORD record
ord-9b69325ebf204563afe7f61b630e0bdf
Source dataset
uspto-grants-2013_09
Patent number
US08530670B2

Reaction notes

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