Hydrochloric Acid → HCID 178516629, compound

HRID 41767Notes

Reaction equation

HRID 41767 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[C:19]([F:21])[CH:18]=[C:17]([F:22])[C:16]=4[F:23])[C:13](=[O:24])[CH:12](C(OCC)=O)[C:11]3=[O:30])=[CH:9][C:4]=2[N:3]=[CH:2]1.Cl>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[C:19]([F:21])[CH:18]=[C:17]([F:22])[C:16]=4[F:23])[C:13](=[O:24])[CH2:12][C:11]3=[O:30])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178470027HCID 178470027, compound

Product 1

HCID 178516629HCID 178516629, compound

Procedure

The compound was synthesized starting from ethyl 1-(1H-benzo[d]imidazol-5-yl)-2,4-dioxo-5-(2,3,5-trifluorophenyl)pyrrolidine-3-carboxylate (which may be prepared in accordance with the procedure described for Intermediate 7; 0.036 g, 0.086 mmol) and 5 N aqueous hydrochloric acid (3 ml) according to the method described in Method 1, step 3.

Workup

  1. customThe compound was synthesized
  2. custommay be prepared in accordance with the procedure

Sources & evidence

ORD record
ord-a806853ea01b49a8be8cd9cf6e314b77
Source dataset
uspto-grants-2013_09
Patent number
US08530670B2

Reaction notes

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